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Package Details

1650

Sample Type :

Blood

Report Delivery :

Same Day

Pre-test Information :

No special preparation is required for the test.

ANTI THYROGLOBULIN ANTIBODY

Tests Included (1)

  • ANTI THYROGLOBULIN ANTIBODY

Item Description

If the Anti TPO autoantibody comes out to be negative but the clinical suspicion of autoimmune thyroid disease is high then one needs to undergo an anti-Tg autoantibody measurement. By detecting these antibodies in the case of neonatal hypothyroidism, the transplacental antibody transfer can be determined. This is useful especially if there is a maternal history of autoimmune thyroiditis.

Information for doctor

This test is used as an adjunct in the diagnosis of autoimmune thyroid diseases: Hashimoto disease, postpartum thyroiditis, neonatal hypothyroidism and Graves disease. In individuals with autoimmune hypothyroidism 30% to 50% will have detectable anti-Tg autoantibodies while 50% to 90% will have detectable anti-TPO autoantibodies. In Graves disease both types of autoantibodies are observed at approximately half these rates. The presence of anti-Tg which occurs in 15% to 30% of thyroid cancer patients could result in misleading Tg results. Anti-Tg may result in both falsely-low and less commonly falsely high serum Tg measurements. Therefore in anti-Tg-positive patients serum Tg measurements should not be used as the sole measurement for thyroid cancer follow-up and should be interpreted with caution.

Synonyms for Test

Anti Tg

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